KMID : 0604520130390030225
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Journal of the Society of Cosmetic Scientists of Korea 2013 Volume.39 No. 3 p.225 ~ p.231
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Novel Encapsulation with New Glyceryl Ester Vesicle Enhances Stability of Nanoemulsion Containing Astaxanthin
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Kim Dong-Myung
Hong Weon-Ki Kong Soo-Sung Lee Un-Yep
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Abstract
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Oil in water nanoemulsion of astaxanthin was prepared by high pressure homogenization. The emulsifying conditionsincluding emulsifier type, concentration and astaxanthin concentration were optimized. Stability of nanoemulsionwas measured using zetasizer, freeze-fracture scanning electron microscope (FF-SEM), particle analyzer and colorimeter.The mean diameter of the dispersed particles containing astaxanthin ranged from 160 to 190 nm. Size distribution wasunimodal and extended from 40 to 200 nm. The nanoemulsion prepared by glyceryl citrate/lactate/linoleate/oleate hadsmaller particle size and narrow size distribution. Stable incorporation of astaxanthin in nanoemulsion was performedand checked using high performance liquid chromatography (HPLC), freeze-fracture scanning electron microscope(FF-SEM). Physical stability of nanoemulsion was not significantly changed during storage at both light and thermalcondition for a month with zeta potential value of -41 mV meaning stable colloid.
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KEYWORD
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nanoemulsion, astaxanthin, high pressure homogenation, zeta potential
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